Open Orphan launches Disease in Motion® platform
(ORPH ) announced that its subsidiary, hVIVO, has officially launched its data-focused ‘Disease in Motion®’ platform which currently spans several conditions.
The specialist pharmaceutical services research organisation outlined that this data-focused platform includes clinical, immunological, virological and digital (wearable) biomarkers.
The platform has multiple infectious disease applications applicable to a wide variety of end users including big tech, wearables, pharma and biotech companies. The Group added that it has plans to expand the number of conditions that the platform covers going forward.
Data from Disease in Motion® is continuously gathered throughout the onset, progression and resolution of an infection which is enabled by hVIVO's challenge study model, it noted.
Open stated that it is committed to volunteer patient data privacy and that data is only collected from fully consented volunteers in accordance with all relevant privacy guidelines.
Commenting on the launch, Cathal Friel, Executive Chairman of Open Orphan said, “The Disease in Motion platform includes data from cutting edge wearables that are applicable to a wide variety of end users including big tech, wearables, pharma and biotech companies.
As volunteers remain under close observation prior to viral challenge, during disease progression and until resolution, data is captured across the full time-course of the infection, yielding possible insights into the body's response to infection. The Disease in Motion platform currently spans several conditions with plans to expand this going forward.”
He said, “As a recognised global leader in supporting the development of therapeutics and vaccines, hVIVO and our team of virological, clinical and regulatory experts are actively in discussion with potential partners to help address the next set of challenges facing humanity."
Shares in Open Orphan have increased by over 55% in value since the beginning of the year, with the stock demonstrating a more than six-fold increase since the start of April 2020. This morning, shares in the company were trading 4.10% higher at 41.74p following the news.
Open Orphan is a rapidly growing Contract Research Organisation and world leader in the testing of vaccines and antivirals through the use of human challenge clinical trials.
The Group comprises two commercial specialist CRO services businesses, hVIVO and Venn Life Sciences and is also building out a valuable data platform business. All businesses are now working closely together to offer upselling and cross selling opportunities.
World Class Facilities
Open has Europe's only 24-bedroom quarantine clinic with onsite virology providing individually isolated rooms and specialist laboratory facilities. The hVIVO facility offers highly specialised virology and immunology laboratory services to support pre-clinical and clinical respiratory drug, antiviral, and vaccine discovery and development.
Largest Test Portfolio
Open Orphan has a leading portfolio of 8 viral challenge study models, which are: 2 FLU, 2 RSV, 1 HRV, 1 Asthma, 1 cough and 1 COPD viral challenge models. As announced in early March 2020, it is rapidly advancing several COVID-19 challenge study models and expects to be helping many COVID-19 vaccine development companies to test their vaccines.
hVIVO works with UK and Irish companies to provide COVID-19 testing to staff to protect staff and customers from a workplace COVID-19 outbreak through its COVID Clear offering.
The company announced that its first volunteer had been dosed with the Codagenix needle free, intranasal COVID-19 vaccine, COVI-VAC as part of a Phase I clinical trial of COVI-VAC currently being carried out by hVIVO, at its facility in the UK.
Rapidly Expanding Market
The market for vaccine development and testing has grown rapidly over the past six months, largely due to the outbreak of Covid-19.
However, ORPH believes Governments and International pharmaceutical companies around the world will be making enormous ‘catch-up investments’ in all types of vaccine development to ensure the effects of any pandemic can be mitigated in the future, which it said should result in the hIVO facility being booked out for months, if not years, in advance going forward.
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